The Centerline Biomedical Intra-Operative Positioning System (IOPS®) technology is an innovative, three-dimensional (3D) GPS-like surgical navigation technology designed to improve visibility during endovascular procedures, thereby decreasing procedure time and reducing radiation exposure.

IOPS received FDA 510(k) clearance and is available in the United States.

The IOPS (Intra-Operative Positioning System) is intended for the evaluation of vascular anatomy as captured via 3D modeling from previously acquired scan data. It is intended for real time tip positioning and navigation using sensor equipped compatible catheters and guidewires used in endovascular interventions in the descending aorta. The system is indicated for use as an adjunct to fluoroscopy. The IOPS does not make a diagnosis.

Centerline Biomedical, Inc. is an innovator in cardiovascular visualization and navigation systems. Founded in 2014, the Company is headquartered in Cleveland, Ohio and was originally innovated at the Cleveland Clinic. The company’s FDA-cleared technology platform, Intra-Operative Positioning Systems, “IOPS®”, enables improved visualization and navigation in endovascular procedures. The IOPS received FDA 510(k) clearance for use in the descending aorta. The company continues investment in development to enhance the current technology platform and expand image guidance in transcatheter procedure applications.

Centerline Biomedical is housed in Cleveland Clinic’s Global Cardiovascular Innovations Center in Cleveland, OH.

Centerline Biomedical was incorporated in 2014.

The press contact can be reached at media@centerlinebiomedical.com

Please contact Indrani Egleston, CFO (indrani.egleston@centerlinebiomedical.com) for all investor relations inquiries.